The present description relates to an isolated population of human placental pluripotent stem cells or an isolated human placental pluripotent stem cell positive for human leucocyte antigen-G (HLA-G), a migration marker and at least one pluripotent stem cell marker. The present description further provides a method for isolating human placental pluripotent stem cells. The method comprising: extracting cells from a human placenta； and isolating cells positive for human leucocyte antigen-G (HLA-G), a migration marker and at least one pluripotent stem cell marker and use thereof. On the other hand, it is likely that this present description is 10 applicable to primates and other animals.
