COMPOSITION POUR L'INHIBITION DE L'ANGIOGENÈSE CONTENANT UN COMPLEXE DE NANOPARTICULE-PROTÉINE À BASE DE CORPS VITRÉ EN TANT QUE SUBSTANCE ACTIVE, ET UTILISATION DE CELLE-CI
Seoul National University R&DB Foundation;Korea Research Institute of Standards and Science
发明人:
KIM, Jeong Hun,JO, Dong Hyun,LEE, Tae Geol
申请号:
EP16824707
公开号:
EP3323411A4
申请日:
2016.07.12
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The present invention relates to a nanoparticle-vitreous body-based protein complex, and more particularly, to a composition for inhibiting angiogenesis which includes the complex as an active ingredient, and a composition for preventing or treating an angiogenesis-related disease or a retinal disease. When the nanoparticle-vitreous body-based protein complex according to the present invention is locally injected into the vitreous body, the complex exhibits significantly excellent binding strength with a vascular endothelial growth factor and thus can inhibit angiogenesis, thus being easily used to prepare a therapeutic agent for preventing, alleviating, or treating retinal and choroidal angiogenesis-related diseases.