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שחרור רכיב רוקחי פעיל בוויסות עצמי
专利权人:
ACURA PHARMACEUTICALS INC.
发明人:
申请号:
IL23871315
公开号:
IL238713D0
申请日:
2015.05.10
申请国别(地区):
IL
年份:
2015
代理人:
摘要:
The present invention relates to an abuse deterrent pharmaceutical composition comprising: a. a pharmaceutically active ingredient; b. an acid soluble ingredient comprising one or more of calcium carbonate, dibasic calcium phosphate, tribasic calcium phosphate, and magnesium hydroxide; and c. a buffering ingredient; wherein the acid soluble component is included in the form of a particle matrix with the active pharmaceutical ingredient, wherein the buffering ingredient is present in an amount sufficient to inhibit dissolution of the particle matrix when the abuse deterrent pharmaceutical composition is ingested in an excess amount.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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