A biopsy forceps includes an end effector with opposing first and second jaws coupled together and configured to move from an open configuration to a closed configuration. Each of the first jaw and the second jaw includes a plurality of teeth having a base. The bases of two adjacent teeth of the first jaw are spaced apart to form a first gap, and the bases of two adjacent teeth on the second jaw are spaced apart to form a second gap. The end effector in the closed configuration may define one or more windows between edges of the first and the second jaws. And, at least one of these windows may include at least a portion of one or both of the first and second gaps.