PHARNACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF THROMBOSIS COMPRISING THE MIXED EXTRACT OF VEGETABLE NATURAL PRODUCTS HAVING THE EFFECT ON REMOVAL OF SWELLING AND HEALTH FUNCTIONAL FOOD FOR PREVENTION OR IMPROVEMENT OF THROMBOSIS COMPRISING THE SAME
The present invention relates to a pharmaceutical composition for preventing or treating/improving thrombosis and a health functional food containing a mixed extract of a plant-based natural product having excellent activity for enhancing swelling, strengthening immunity, and enhancing metabolism as an active ingredient. To prevent thrombosis through blood coagulation inhibitory activity and platelet aggregation inhibitory activity containing hot water extract of a mixture of vegetable natural products including parsley, burdock, pumpkin, plantain leaves, red beans, black beans, jujube and ginger as an active ingredient It relates to a pharmaceutical composition for treatment / improvement and a dietary supplement. Mixed extracts of vegetable natural products including parsley, burdock, pumpkin, plantain leaves, red beans, black beans, jujube and ginger as an active ingredient of the antithrombotic composition of the present invention, as demonstrated through the examples of the present specification, total poly While the content of phenol and total flavonoid is very high, the content of total sugar and reducing sugar is very low, and at the same time, it shows anticoagulant activity and platelet aggregation inhibitory activity by inhibition of blood clotting-related enzymes and blood coagulation factors. It does not show hemolytic activity at all, has excellent thermal stability, and does not show any loss of blood clotting-related enzymes and blood clotting factor inhibitory effects even in acidic conditions at pH 2 and in plasma.Thus, thrombosis such as ischemic stroke and hemorrhagic stroke can be prevented by improving blood circulation. It is expected that it can be used for prevention and treatment, and the active ingredient is processed into various forms such as extracts, powders, pills, tablets, etc., and has an excellent effect that can be prepared in a form that can be taken at all times. It is a very useful invention.본 발명은 붓기 제거, 면역력 강화, 신진대사 증강 활성이 우수한