ELENI DOKOU,SHAHLA JAMZAD,JOHN P. CAESAR, JR.,MAJED FAWAZ,LAURA DAS,CHONG-HUI GU,PATRICIA NELL HURTER,MEGHNA JAI ISRANI,MEGHAN M. JOHNSTON,DRAGUTIN KNEZIC,ANDREW G. KUZMISSION,HONGREN WANG
申请号:
US13779654
公开号:
US20130224293A1
申请日:
2013.02.27
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to pharmaceutical compositions containing a solid dispersion of N—[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide including formulations of the solid dispersions into powders, granules and mini-tablets, methods for manufacturing and processing the powders, granules and mini-tablets, and methods for treating cystic fibrosis employing the pharmaceutical composition.