Xuqing Zhang,Marta C. Abad,Alan C. Gibbs,Gee-Hong Kuo,Lawrence C. Kuo,Fengbin Song,Zhihua Sui
申请号:
US13091344
公开号:
US08822447B2
申请日:
2011.04.21
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention is directed to substituted indazole compounds of formula (I)pharmaceutical compositions of these compounds and methods of use thereof. The compounds of the present invention are ketohexokinase (KHK) inhibitors, useful for treating or ameliorating a KHK mediated metabolic disorders and/or diseases such as obesity, Type II diabetes mellitus and Metabolic Syndrome X.