Jaap Willem Back,Ronald Boshuizen,Wouter Cornelis Puijk,Johan Turkstra
申请号：
US15751169
公开号：
US20180237529A1
申请日:
2016.08.10
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides novel humanized anti-human CCR7 antibodies and compositions comprising such antibodies. The antibodies and compositions are useful in the treatment of a cancer of which the tumour cells express a CCR7 receptor, in the treatment of inflammatory conditions, conditions or complications arising from tissue or organ transplantations, and conditions or complications arising from or associated with fibrosis. The invention further provides nucleic acid molecules encoding the anti-CCR7 antibodies, cells expressing the anti-CCR7 antibodies and methods for producing the anti-CCR7 antibodies.
