用於治療精神病和神經變性疾病的作為NACHR胆碱能配體的(1-氮雜-雙環[3．3．1]壬-4-基)-[5-(1H-吲哚-5-基) -雜芳基]-胺

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专利权人:

NOVARTIS AG

发明人:

FREDERIKSEN, MATHIAS,FEUERBACH, DOMINIK,HURTH, KONSTANZE,KOLLER, MANUEL,ROY, BERNARD, LUCIEN

申请号：

HK09101354.9

公开号：

HK1121443B

申请日:

2009.02.13

申请国别(地区):

HK

年份:

2012

代理人:

摘要：

The present invention relates to compounds of formula (I) wherein n represents 0, 1, 2, 3, 4 or 5, R represents independent from each other hydroxyl, cyano, nitro, halogen, alkyl, alkoxy alkylcarbonyl, alkoxycarbonyl, alkylamine, dialkylamine, alkylcarbonylamine, alkylcarbamate Y represents one of the following groups: in free base or acid addition salt form, to processes for their production to pharmaceutical compositions comprising them and for use as cholinergic ligands of n-AChR.

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