ARIZONA BOARD OF REGENTS ON BEHAFT OF ARIZONA STATE UNIVERSITY
发明人:
TAO, Nongjian
申请号:
WO2018US33520
公开号:
WO2018213790(A2)
申请日:
2018.05.18
申请国别(地区):
世界知识产权组织国际局
年份:
2018
代理人:
摘要:
An apparatus for label-free analysis of molecules, including interactions and reactions of the molecules, is disclosed. The apparatus is based on detecting molecule movement under the influence of an external electric field. The apparatus is able to achieve sensitive detection of molecular binding to proteins or other molecules, and conformational changes of proteins or other molecules and biochemical reactions of the proteins or other molecules. Applications of the apparatus include screening of drug molecules, kinetic analysis of posttranslational modification of proteins, and small molecule-protein interactions.