The present invention provides crystal form D of Baricitinib phosphate, characterized in that, under the measurement of X-ray powder diffraction, the 2θ of X-ray diffraction pattern (XRPD) includes feature peaks at 3.68° ± 0.20°, 7.40° ± 0.20°, 14.79° ± 0.20°, and 18.28°± 0.20. Crystal form D of Baricitinib phosphate of the present invention can used as an active pharmaceutical ingredient for pharmaceutical composition for curing autoimmune diseases, especially rheumatoid arthritis.本發明提供一種巴瑞克替尼(Baricitinib)磷酸鹽晶型D,其特徵在於使用X射線粉末繞射時,其XRPD圖譜在2θ值包含3.68°±0.20°、7.40°±0.20°、14.79°±0.20°、18.28°±0.20處具有特徵性波峰。本發明之巴瑞克替尼磷酸鹽晶型D,其可作為用於治療自體免疫疾病之藥物組合物中的藥物活性成分,特別係治療類風濕性關節炎。
