Liangfang Zhang,Che-Ming Jack Hu,Ronnie H. Fang,Brian T. Luk,Kuei-Chun Wang,Shu Chien
申请号：
US15737566
公开号：
US20180153821A1
申请日:
2016.06.07
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to prevention and/or treatment of diseases or disorders associated with a damaged or leaky vasculature in a subject. The present invention provides for methods, combinations and pharmaceutical compositions for preventing and/or treating a disease or disorder associated with a damaged or leaky vasculature in a subject, using, inter alia, an effective amount of a nanoparticle comprising an inner core comprising a non-cellular material, an outer surface comprising a cellular membrane derived from a platelet； and optionally an agent for preventing, treating, diagnosing, or prognosing the disease or disorder and/or monitoring prevention or treatment of the disease or disorder. Exemplary diseases or disorders include hemorrhage (bleeding), cardiovascular diseases or disorders, diseases or disorders associated with narrowing of a blood vessel, tumors or cancers.
