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METHOD OF DETERMINING DEGREE OF ACTIVITY OF ENDOGENOUS UVEITES IN CHILDREN BASING ON DATA OF CORNEAL CONFOCAL MICROSCOPY
专利权人:
FEDERALNOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "MOSKOVSKIJ NAUCHNO-ISSLEDOVATELSKIJ INSTITUTGLAZNYKH BOLEZNEJ IMENI GELMGOLTSA" MINISTERSTVA ZDRAVOOKHRANENIJA I SOTSIALNOGO RAZVITIJA ROSSIJSKOJ F
发明人:
KATARGINA LJUDMILA ANATOLEVNA,Катаргина Людмила Анатольевна,SHESTOVA JULIJA PAVLOVNA,Шестова Юлия Павловна,DENISOVA EKATERINA VALEREVNA,Денисова Екатерина Валерьевна
申请号:
RU2012129300
公开号:
RU2495616C1
申请日:
2012.07.11
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to ophthalmology, and can be used for determination of degree of activity of endogenous uveites in children. For this purpose eye cornea is examined by confocal microscopy. Presence of epithelium and stroma edema, characteristics of keratocytes is obtained, presence of sparsity and folds of stroma is detected, presence of hyporeflective defects of endothelium, expansion of intercellular spaces, local hyperreflectiveness with blurring of boundaries of endothelial cells, focal tractions and edema of endotheliocytes is detected. Remission is determined if edema of epithelium and stroma is absent, single "activated" keratocytes in field of vision in one of stroma layers and precipitates with clear boundaries are present. In case of mild edema of epithelium and stroma in combination with one or more of the following signs: "activated" or "agglutinated" keratocytes from 2 to 5 in field of vision in one of stroma layers, presence of stroma sparsity, precipitates with unclear boundaries, hyporeflective defects of endothelium to 5 in field of vision, single expansions of intercellular spaces, minimal local hyperreflectiveness with blurring of boundaries of endothelial cells, subactive uveitis is determined. In case of moderate edema of epithelium and stroma in combination with one or more of the following signs: "activated" and "agglutinated" keratocytes more than 5 in field of vision in one of stroma layers, presence of sparsity and folds of stroma, precipitates with unclear boundaries, hyporeflective defects of endothelium from 5 to 20 in field of vision, expansions of intercellular spaces from 2 to 5 in field of vision, moderate local hyperreflectiveness with blurring of boundaries of endothelial cells and focal cell tractions, subacute uveitis is determined. In case of manifested edema of epithelium and stroma in combination with one or more of the following signs: "activated" and "agglomerated" keratocytes
来源网站:
中国工程科技知识中心
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