Massachusetts Eye and Ear Infirmary;Children's Medical Center Corporation
发明人:
Demetrios G. Vavvas,Joan W. Miller,Larry Benowitz
申请号:
US14930501
公开号:
US10022419B2
申请日:
2015.11.02
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided are methods for promoting axon regeneration of a Central Nervous System (CNS) neuron and promoting nerve function following injury to a CNS neuron, for example, brain and/or spinal cord injury. Axon regeneration in a CNS neuron or nerve function following injury to a CNS neuron can be promoted by administering a necrosis inhibitor either alone or in combination with an apoptosis inhibitor to a subject suffering from a CNS disorder, wherein a symptom of the CNS disorder is axon degeneration.