LEE, KYUNG IK,JUNG, YOUNG HEE,SONG, JI YOUNG,JUN, SEUNG AH
申请号：
CA3029175
公开号：
CA3029175A1
申请日:
2017.06.30
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
The present invention relates to a novel substituted pyrazole derivative, having the effect of inhibiting the serine/threonine kinase activity, targeting the receptor ALK5 of TGF-ß. A pharmaceutical composition containing a compound of the present invention as an active ingredient can be usefully used in the treatment and/or prevention of cancer, an autoimmune disease, a fibrotic disease, an inflammatory disease, a neurodegenerative disease, an infectious disease, a pulmonary disease, a cardiovascular disease or a metabolic disease or other diseases associated with a decrease in TGF family signaling activity.
