The subject matter of the present invention is a system for measuring interface pressure exerted on the skin, that is in particular of use in compression therapy, characterized in that it comprises: —a supporting member bearing sensors, including at least two pressure sensors spaced out on the supporting member in order to make it possible to measure the pressure exerted at two predetermined positions; —an electronic system connected to the sensors and capable of acquiring the values simultaneously measured by these sensors; and in that each pressure sensor comprises a transducer element, which is preferably substantially flat, said transducer element having a surface intended to come into contact with the skin in the operating position, either directly or by means of a layer of a material covering said surface of the transducer, the elastic modulus of compression of said transducer or of said intermediate layer, measured at the surface intended to come into contact with the skin, being between 30 and 500 kPa, preferably between 80 and 400 kPa and more preferably between 200 and 400 kPa. Use: compression therapy.