Provided is a method for preparation of a synbiotic having miracle fruit and probiotics, including the following steps: (1) preparing miracle fruit and mixing the miracle fruit with water to obtain a miracle fruit solution (2) adjusting a pH value of the miracle fruit solution to range from 5 to 8 (3) adding milk powder to the miracle fruit solution after adjusting the pH value to obtain a miracle fruit matrix and (4) culturing the miracle fruit matrix and the probiotics to obtain the synbiotic having the miracle fruit and the probiotics. Also provided is the synbiotic having miracle fruit and probiotics prepared by the abovementioned method. Also provided is a tablet of synbiotic having miracle fruit and probiotics comprising synbiotic powder, a first fruit powder, and an excipient. The synbiotic having miracle fruit and probiotics can significantly increase SOD-like activity for anti-oxidation.