MENET CHRISTEL JEANNE MARIE,DOYON JULIEN GEORGES PIERRE OLIVIER,ALLART BRIGITTE,CLAES PIETER ISABELLE ROGER,TRICARICO GIOVANNI ALESSANDRO,DE WACHTER MAXIM MARIA PAUL
申请号:
IN201727038995
公开号:
IN201727038995A
申请日:
2017.11.02
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
A compound according to Formula (I): wherein R L Cy R R R and R are as described herein. The present invention relates to novel compounds according to Formula I that antagonize GPR84 a G protein coupled receptor that is involved in inflammatory conditions and methods for the production of these novel compounds pharmaceutical compositions comprising these compounds and methods for the prevention and/or treatment of inflammatory conditions pain neuroinflammatory conditions neurodegenerative conditions infectious diseases autoimmune diseases endocrine and/or metabolic diseases cardiovascular diseases leukemia and/or diseases involving impairment of immune cell functions by administering a compound of the invention.