XIA, YAN,MCIVER, EDWARD GILES,SONG, YANG,XU, YUANYUAN,ZHU, LIN,CHU, CHUNJUN,WU, LING,LIU, MIAO,BRYANS, JUSTIN STEPHEN
申请号：
CA3026844
公开号：
CA3026844A1
申请日:
2017.06.13
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Provided are a substituted tricyclic herteocyclic compound of formulaI or a stereoisomer, a tautomer, an N-oxide, a hydrate, a solvate, ametabolite,a pharmaceutically acceptable salt, ester or a prodrug thereof, apharmaceuticalcomposition including the same and uses thereof. The substituted tricyclicherteocyclic compounds and the pharmaceutical compositions comprising thecompounds disclosed herein can be used for treating a disorder caused by atleastone of cancer and neurodegenerative diseases. Further the compounds and thepharmaceutical compositions comprising the compounds disclosed herein canbe also used for preventing or treating a disorder caused by, associated withoraccompanied by any abnormal kinase activity.
