INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION;HOFFMANN-LA ROCHE INC.
发明人:
Richard D. DiMARCHI,David L. SMILEY,Konrad H. BLEICHER,Eric A. KITAS
申请号：
US15830158
公开号：
US20180105569A1
申请日:
2017.12.04
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Provided herein are glucagon analogs which exhibit potent activity at the GIP receptor, and, as such are contemplated for use in treating diabetes and obesity. In exemplary embodiments, the glucagon analog of the present disclosures exhibit an EC50 at the GIP receptor which is within the nanomolar or picomolar range.
