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Multi-layered transdermal system with triazine UV absorber
专利权人:
Thomas Langguth
发明人:
Thomas Langguth,Stefan Bracht
申请号:
US11416148
公开号:
US08962013B2
申请日:
2006.05.02
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The UV-stable solid transdermal therapeutic system (TTS) with UV absorber for photosensitive active pharmaceutical ingredients has a backing layer (1), at least one active ingredient-containing matrix (2), and a detachable protective film (3). Optionally an adhesive layer (4) and a separating layer (5) are introduced between the backing layer (1) and the at least one active ingredient-containing matrix (2). At least one hydroxyphenyltriazine compound acting as UV absorber is embedded in the backing layer (1), in the active ingredient-containing matrix (2), or in the adhesive layer (4). The TTS according to the invention achieves high stability at low concentrations of UV absorber, preferably 0.5 to 3% (m/m), so as to reduce or avoid skin irritation.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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