A topical composition includes a polymer matrix containing sodium hyaluronate and a nonionic polymer, the polymer matrix being suspended in a liquid medium; and a therapeutically effective amount of a nutraceutical entity dispersed in suspension within the polymer matrix, wherein the molar ratio of the sodium hyaluronate to the nonionic polymer is 1:0.5 to 4, the sodium hyaluronate being present in amounts of about 2.0% to about 3.5% by weight of the composition. Other topical compositions and uses thereof are disclosed.