Joel Z. Melnick;Sammy A. Agudoawu;Samir P. Tabash;Jay A. White
发明人:
Jay A. White,Samir P. Tabash,Sammy A. Agudoawu,Joel Z. Melnick
申请号:
US14213285
公开号:
US20140349979A1
申请日:
2014.03.14
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A stabilized formulation for controlled release of a vitamin D compound is disclosed. The formulation comprises one or both of 25-hydroxyvitamin D2 and 25-hydroxyvitamin D3 and a cellulosic compound. The stabilized formulations exhibit a stable dissolution profile following exposure to storage conditions and demonstrate improved pharmacokinetic parameters compared to unstabilized formulations.