An expandable biopsy device and a method of obtaining a biopsy sample are provided. The expandable biopsy device includes an expandable portion including an expandable plate member and a cable operably connected to the expandable plate member. The expandable plate member has a substantially flattened configuration and an expanded configuration where the expanded configuration is longitudinally elongated relative to the flattened configuration. The flattened configuration has a first diameter. The expandable biopsy device also includes a cutting portion including a blade and a housing. The blade is positionable at least partially within the housing and the blade has a second diameter. The housing includes an opening and a cavity formed within housing. The second diameter of the blade is greater than the first diameter of the expandable plate member in the substantially flattened configuration.