ALBERT, EKATERINA,NELSON, JENNIFER LEIGH,SEADEEK, CHRISTOPHER SCOTT,REINEKE, KARL,JONAS, MARCO,IYER, SUBA,SUN, XUFENG,CUTSHALL, NEIL S.,GAGE, JENNIFER LYNN,LITTLE, THOMAS L.,LUKE, WAYNE DOUGLAS,BROT,
申请号:
CA3003611
公开号:
CA3003611A1
申请日:
2016.11.04
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention relates to a novel variable hydrate crystalline form of 1-(5-(4-chloro-3,5-dimethoxyphenyl)furan-2-yl)-2-ethoxy-2-(4-(5-methyl-1,3,4-thiadiazol-2-yl)phenyl)ethanone, methods for the preparation thereof, pharmaceutical compositions thereof and their use in the inhibition of PDE10.