Rao Galla Chandra,Connelly Mark C.,Garcia-Blanco Mariano A.,Armstrong Andrew J.,Bitting Rhonda L.
申请号:
US201314765071
公开号:
US10161939(B2)
申请日:
2013.05.31
申请国别(地区):
美国
年份:
2018
代理人:
Michael Best & Friedrich LLP
摘要:
Provided are methods for detecting or isolating circulating tumor cells (CTCs) in a subject. The methods may include detecting the expression of at least one epithelial mesenchymal transition (EMT) biomarker. Further provided are kits for detecting or isolating CTCs. The kits may include antibodies to at least one EMT biomarker. Further provided are methods of predicting the responsiveness of a subject to a cancer drug, methods of targeting delivery of a cancer drug in a subject, methods of providing a cancer prognosis to a subject, and methods for following the progress of cancer in a subject.