A method for physiological measurement and a portable electronic device executing the method are provided. The portable electronic device includes a key and a display. The method includes the steps of transmitting at least one trigger signal when the key is pressed, transmitting a first light signal through the key to the outside of the key according to the trigger signal, receiving a second light signal through the key, and obtaining physiological information according to the second light signal. The second light signal is the first light signal reflected back by an object.一種生理量測方法與執行上述方法的攜帶式電子裝置。攜帶式電子裝置包括按鍵和顯示器。上述生理量測方法包括以下步驟:在按鍵受壓時發出至少一觸發信號,根據觸發信號而透過按鍵向按鍵的外側發出第一光信號,透過按鍵接收第二光信號,以及根據第二光信號獲得生理資訊。其中第二光信號為第一光信號遇到物件所反射回的光信號。405~455‧‧‧方法步驟