PROBLEM TO BE SOLVED: To provide effective preventive or therapeutic means for multiple organ failure, particularly multiple organ failure caused by acute renal insufficiency.SOLUTION: This invention relates to preventive or therapeutic agent for multiple organ failure caused by acute renal insufficiency, comprising adrenomedullin or its modification having multiple organ failure inhibitory activity, or their salt, or their solvate as an active ingredient.【課題】多臓器不全、特に急性腎障害に起因する多臓器不全の有効な予防又は治療手段を提供する。【解決手段】本発明は、アドレノメデュリン若しくは多臓器不全の抑制活性を有するその修飾体又はそれらの塩、或いはそれらの溶媒和物を有効成分として含有する、急性腎障害に起因する多臓器不全の予防又は治療薬に関する。【選択図】なし
