Gastro-duodenal implants of the present disclosure are configured to resiliently absorb / redistribute gastrointestinal forces, and can include a first retention structure configured to reside in the stomach, and a second retention structure configured for positioning adjacent to the pyloric sphincter on the pyloric opening's duodenal side. Resilient coupling members (e.g., one or more springs) can resiliently bias the first portion away from the second portion (e.g., to maintain the first portion at a default separation distance away from the second portion or the pyloric sphincter). The first portion can be deformable, such as by way of resilient elements that couple frame members, or ellipsoidal / toroidal elements within a flexible assembly. In an embodiment, the first portion includes a compressible fluidly distortable structure configured to adaptively deform (e.g., compress or expand as a result of fluid displacement within the first retention structure).
