BENGHEZAL, MOHAMMED,SCHOEP, TOBIAS,FULURIJA, ALMA,BERG, DOUGLAS E.,MARSHALL, BARRY
申请号：
EP11797396
公开号：
EP2585584A4
申请日:
2011.06.24
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
The present invention relates to a means of controlling infection persistence of Helicobacter pylori (H. pylori). In particular, the present invention relates to an isolated, genetically modified Helicobacter pylori comprising a functional urease, wherein the contiguous amino acid sequence between amino acid 529 and amino acid 555 of SEQ ID NO:1 is altered to produce said modified Helicobacter pylori which is unable to establish or maintain a persistent infection.
