HOWBERT, JAMES, JEFFRY,HERSHBERG, ROBERT,BURGESS, LAURANCE E.,DOHERTY, GEORGE A.,EARY, CHARLES TODD,GRONEBERG, ROBERT D.,JONES, ZACHARY,LYSSIKATOS, JOSEPH P.,YANG, HONG WOON
申请号:
EP12733896
公开号:
EP2663555A4
申请日:
2012.01.12
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, fibrotic disease, cardiovascular disease, infectious disease, inflammatory disorder, graft rejection, or graft-versus-host disease.