The invention relates to a cocktail against Aids, consisting of a commercially available anti-tumoral drug (1), such as doxorubicin, idarubicin, etoposide, chlorambucil, cisplatin, melphalan or bortezomib, a P-glycoprotein inhibitor (2), such as tariquidar, cetoconazol, verapamil, amiodarone or quinidine, and a commercially available antiviral agent of the viricidal type (3) which acts directly on the virus, such as N,N-dichloro-2,2-dimethyltaurine (NVC-422) or the HIVcide nanoviricide, and designed to combat and completely eliminate the Aids virus from the organism.