Ross Wentworth Stephens,Gregory David Tredwell,Karen Joanne Knox,Lee Andrew Philip,Rebecca Greenlees,Keira Beattie
申请号：
US16469244
公开号：
US20200038528A1
申请日:
2017.12.15
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention relates to a radiolabelled material comprising a polymer, a radioactive isotope, and an immobilizing agent, wherein the immobilizing agent is capable of immobilizing the radioactive isotope on or in the polymer, and wherein the immobilizing agent is a macromolecule comprising a polycation with multiple pendant metal-chelating side-chains. The invention also relates to a process for making a radiolabelled material, to use of a radiolabelled material for the preparation of medicaments for treating cancer and/or for radiation imaging and to use of a radiolabelled material in the treatment of cancer. There is further described use of an immobilizing agent to immobilize a radioactive isotope on or in a polymer.
