An endoscope puncture needle is provided with: an outer sheath; a needle tube arranged inside the outer sheath; an operation section which advances and retracts the needle tube with respect to the outer sheath; a proximal-end-side inner tube arranged at an inside of a proximal end of the outer sheath; and a distal-end-side inner tube arranged inside a distal end section of the outer sheath and has an inner circumferential surface that is relatively harder than the proximal-end-side inner tube. The operation section is provided with an operation main body, a needle slider, and an engaging mechanism. When the needle slider is engaged to the operation main body, a distal end of the needle tube is arranged inside the distal-end-side inner tube.