ЛИ Чиан Цзя (US),ЛЕДЖЕТТ Дэвид (US),ЛИ Ючжи (US),ЛИ Вэй (US)
申请号：
RU2012144420/13
公开号：
RU2012144420A
申请日:
2011.03.21
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. A method of treating cancer in a human, which method comprises administering to a subject in need thereof a therapeutically effective amount of a compound strukturyili a pharmaceutically acceptable salt, solvate, hydrate or prodrug, wherein the compound is administered to a subject at a total daily dose ranging from about 20 mg to about 2000 mg.2. Cancer treatment method for a human, which method comprises administering to the subject a therapeutically effective amount of a compound strukturyili a pharmaceutically acceptable salt, solvate, hydrate or prodrug, wherein the compound is administered to a subject at a dosage sufficient to achieve a blood of an individual compound concentration of at least 1 0 uM or more of at least two hours, and wherein the concentration of the individual compound in blood is greatly reduced in the range of not more than 24 chasov.3. A method according to claim 1, wherein the compound is administered to a subject at a total daily dose ranging from about 400 mg to about 1000 mg.4. A method according to claim 1, wherein the compound is administered to a subject once daily dose in the range of from about 20 mg to about 2000 mg ezhednevno.5. A method according to claim 1, wherein the compound is administered in two doses of the individual sutki.6. A method according to claim 5, wherein each dose is in the range from about 200 mg to about 500 mg twice a sutki.7. A method according to claim 5, wherein each dose is about 500 mg twice a sutki.8. A method according to claim 1, wherein the compound is administered to a subject in three dozah.9 allowance. The method of claim 8, wherein each dose is in the range from about 200 mg to about 500 mg thrice sutki.10. A method according to claim 1, wherein the compound1. Способ лечения рака у человека, где способ включает введение нуждающемуся в этом индивидууму терапевтически эффективного количества соединения структурыили его фармацевтически приемлемой соли, сольвата, гидрата или пролекарственного с
