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OXADIAZOLINE AGENTS FOR MODULATING EXPRESSION OF EXOGENIC GENES FROM AN ECDYSON RECEPTOR COMPLEX
专利权人:
INTREXON CORPORATION
发明人:
HORMANN, ROBERT, EUGENE,CHORTYK, ORESTES,LE, DAT, PHAT
申请号:
DK04775787
公开号:
DK1601354T3
申请日:
2004.02.20
申请国别(地区):
DK
年份:
2014
代理人:
摘要:
The present invention relates to non-steroidal ligands for use in nuclear receptor-based inducible gene expression system, and a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding domain; a transactivation domain; and a ligand is contacted with a DNA construct comprising: the exogenous gene and a response element; wherein the exogenous gene is under the control of the response element and binding of the DNA binding domain to the response element in the presence of the ligand results in activation or suppression of the gene.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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