FRYDMAN, BENJAMIN,MARTON, LAURENCE J.,REDDY, VENODHAR K.,VALASINAS, ALDONIA,BLOKHIN, ANDREI V.,BASU, HIRAK S.
申请号:
CA2371625
公开号:
CA2371625C
申请日:
2000.04.27
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Novel conformationally restricted polyamine analogs are provided, as well ascompositions comprising these novel polyamine analogs. Methods of using thenovel polyamine analogs in treatment of diseases such as cancer are alsoprovided. Also provided is a method of delivering these analogs specificallyto tumor cells by covalently attaching polyamine analogs to porphyrincompounds, along with novel polyamine-porphyrin covalent conjugates.