BROWN, DEAN,DAMEWOOD, JAMES R,HULSIZER, JAMES,MUIR, JAMES CAMPBELL,PIERSON JR, M EDWARD,SHENVI, ASHOKKUMAR BHIKKAPPA,WESOLOWSKI, STEVEN,WIDZOWSKI, DAN,WOOD, MICHAEL,EDWARDS, PHILIP
申请号:
NZ59061609
公开号:
NZ590616A
申请日:
2009.06.18
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed is a compound of formula I or a pharmaceutically acceptable salt thereof, wherein Z is H, -C(=O)-R1, -C(=O)OR1, -C(=O)OCH2, -CH(R1)-NHC(=O)R2, -C(=O)OCHR2OC(=O)R3, -CR1=CR2 or -CH=CHC(=O)R4, wherein R1, R2, R3 and R4 are each independently at each occurrence alkyl, cycloalkyl, aryl, hereroaryl or heterocycloalkyl, e.g. a compound where Z is H, that is 2-fluoro-11-(piperazin-1-yl)dibenzo [b,f][1,4]thiazepine. The intended use of the compounds is for treating bipolar disorders, mood disorders, anxiety disorders, schizophrenia and other psychotic disorders.