您的位置: 首页 > 农业专利 > 详情页

Liposomal Delivery Systems for Oxaliplatin and in Dual Drug Delivery in Combination with Chemo-sensitizing and Chemo-therapeutic agents
专利权人:
THE AMERICAN UNIVERSITY IN CAIRO
发明人:
Tamer Shoeib,Ayat Zein-elabedeen Mohamed
申请号:
US16098509
公开号:
US20190307690A1
申请日:
2017.05.02
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A liposomal delivery composition to be administered through intravenous injection is provided for the treatment of cancer. The delivery composition has a liposome composition with therein encapsulated a first cancer drug (e.g. oxaliplatin) and a second cancer drug (e.g. ascorbic acid or satraplatin). The liposomal delivery composition has negative surface potentials resulting in an encapsulation efficiency for e.g. of oxaliplatin of about 20-25%. The liposomal delivery composition has a particle size of less than 200 nm. The liposomal delivery offers protection of the drug cargo, which reduces their non-intentional and non-pharmacological interactions thus reducing side effects and increases efficacy. Increased efficacy reduces the amount of drug given to a patient, which would reduce healthcare cost. The combinatory approach of two different drug cargos within the same liposome delivery composition allows for the synergistic action of these drugs.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充