KRISHNAN, LAKSHMI,SPROTT, DENNIS,WHITFIELD, DENNIS
申请号：
CA2647060
公开号：
CA2647060C
申请日:
2007.03.30
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Archaeal lipid adjuvants are synthesized by chemically coupling various carbohydrates or anionic polar groups to the free hydroxyl(s) of archaeal lipid cores. Chemically stable lipid cores such as saturated archaeol and caldarchaeol are obtained from appropriate Archaea. Archaeosome lipid vesicles are formulated from the synthetic lipids selected to serve as antigen carriers that target antigen-presenting cells and promote an appropriate immune response to the antigen.
