PROF J MALA,DR CHITRA R CHANDRAN,DR I KANNAN,ISWARYA K
申请号：
IN1797/CHE/2015
公开号：
IN2015CH01797A
申请日:
2015.04.06
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
This invention relates to a new pharmaceutical composition for treatment of urinary tract infections. The present invention generally relates to the fields of bacteriology and infectious diseases. This invention relates to the novel method of inhibiting, preventing or treating bacterial infections. The present invention relates to the inhibition of virulence factor of bacteria and thereby reduction of its virulence. More specifically, it relates to inhibitors of certain bacterial mechanisms and bacterial infection treatments using these inhibitors. are 2-(4-ethoxy-3-hydroxyphenyl)-3- hydroxy-5,6,7-trimethoxy-4H-chromen-4-one, 2-(4-ethoxy-5-hydroxy-2,3- dimethylphenyl)-3-hydroxy-5,6,7-trimethoxy-4H-chromen-4-one, 3,5-dihydroxy-2-{3- hydroxy-4-[(2-hydroxypropan-2- yl)oxy]phenyl}-6,7dimethoxy-8-methyl-4H-chromen- 4-one and 5-hydroperoxy-3-hydroxy-2-{3-hydroxy-4-[(2-hydroxypropan-2- yl)oxy]phenyl}-6,7-dimethoxy-8-methyl-4H-chromen-4-one. These inhibitors can be excellent drug candidate in the treatment of the cases of Urinary Tract Infection.
