A device and method for analyzing of a disturbed pattern of pulse wave front results in a non-invasive, real-time diagnostic tool of arterial vascular performance on both a global and regional scale. The device provides a single number quantifying how well the arterial tree as a whole is coupled to receive and distribute a stroke volume of a single heartbeat. Changing heart rate, contractility, volume status, and afterload will change stroke volume and ejection time. Different vasculatures with different properties (e.g., size and intrinsic stiffness) will be best matched for different stroke volumes and ejection times to provide optimal coupling. The device will allow finding the optimal set of parameters for individual patient.
