Systems and methods for operating an imaging system to perform Cephalometric imaging. The imaging system includes a column, an upper shelf pivotably coupled to the column, a rotating part coupled to the upper shelf and linearly translatable along a length of the upper shelf in a direction radial to the column, a first x-ray source coupled to the rotating part, and an x-ray detector coupled to the rotating part on an opposite side of a first imaging volume from the first x-ray source. A center position of the Cephalometric patient support is determined relative to the imaging system in at least two dimensions by scanning the imaging volume while adjusting a pivot angle of the upper shelf and by scanning the imaging volume while adjusting a linear position of the rotating part along the upper shelf.
