The present invention relates to an anti-obesity composition containing a fermented medicinal herb as an active component. More specifically, the present invention is characterized by producing a fermentation extract by selecting one of the black ginseng, Eucommia ulmoides leaves, Orostachys japonica leaves, and Orostachys japonica flowers, which relates to a method for manufacturing the anti-obesity composition containing the fermented medicinal herb as the active component having an anti-obesity effect by weight loss, inhibition of fat accumulation in tissues (testis peripheral, perinephric, mesenteric peripheral), inhibition of fat cell distribution and size, abdominal fat accumulation inhibition, hepatic fat accumulation inhibition, lipid value (TC, LDL, HDL, TG) reduction, immunity-boosting and inflammation suppression, inhibition of the expression of adiponectin, PPAR-&gamma；, C/EBP&alpha；, and leptin, and recovery of expression of Sirt-1.COPYRIGHT KIPO 2020본 발명은 발효약초를 유효성분으로 함유하는 항비만 조성물에 관한 것이다.보다 구체적으로, 본 발명은 흑삼, 두충잎, 와송잎, 와송꽃 중 1종을 선택하여 발효 추출물을 생성하는 것을 특징으로 하며, 체중감량, 조직(고화주위, 신장주위, 장간막주위) 내 지방축적 억제, 지방세포 분포 및 크기 억제, 복부지방축적 억제, 간조직내 지방축적 억제, 지질(TC,LDL,HDL,TG)수치 감소, 면역증강 및 염증억제, adiponectin, PPAR-γ, C/EBPα 및 leptin의 발현억제, Sirt-1의 발현회복에 의한 항비만 효능을 가지는 발효약초를 유효성분으로 함유하는 항비만 조성물의 제조방법에 관한 것이다.
