ABSTRACT A chewing gum comprising 1-10% of a hydrophilic polymer, 0.1-5% of a surfactant to stabilize the formulated solution, a plasticizer of 10-50% (w/w) of the hydrophilic polymer, wherein the hydrophilic polymer, the surfactant and the plasticizer forms a thin film and 1-4 % of nicotine as an active drug component that forms an aqueous suspension within the thin film, wherein the nicotine rapidly permeates through a buccal mucosal membrane leading to a rapid surge in blood and brain levels of the nicotine which suppresses craving for consumption of tobacco products. The hydrophilic polymer comprises hydroxy propyl methyl cellulose (HPMC) which controls the release of the nicotine into the digestive tract and helps in increased bioavailability of the nicotine. The surfactant comprises Tween 80 as a stabilizer and/or an emulsifier whereas the plasticizer comprises poly ethyl glycol (PEG-400) that makes the hydrophilic polymer more pliable and soft.
