A method of dispensing a therapeutic fluid from a line includes providing aninlet line connectable to an upstream fluid source. The inlet line is indownstream fluid communication with a pumping chamber. The pumping chamber hasa pump outlet. The method also includes actuating a force application assemblyso as to restrict retrograde flow of fluid through the inlet whilepressurizing the pumping chamber to urge flow through the pump outlet. Acorresponding system employs the method.