Kaulina, Larisa,Zemribo, Ronalds,Weil, Tanja,Erdmane, Elina,Parsons, Christopher Graham Raphael,Dekundy, Andrzej,Gutcaits, Aleksandra,Kauss, Valerjans,Fotins, Juris,Nagel, Jens,Jatzke, Claudia,Muller,
申请号:
AU2007280428
公开号:
AU2007280428B2
申请日:
2007.08.03
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Substituted pyrazolopyrimidine derivatives of formula (I) wherein Y,Y, Y, Y represent N or C-, whereby at least twoof the groups Y to Y denote a carbon atom, R representschloro or bromo, R to R7 represent e.g. hydrogen, methyl or ethyl;and R and R independent ly represent e.g. hydrogen orC-Calkyl, are potent mGluR5 modulators and are usefulfor the prevention of acute and chronic neurological disorders.