WALKER, KENNETH W.,GEGG, COLIN V., JR.,HECHT, RANDY I.,BELOUSKI, EDWARD J.,LI, YUE-SHENG,MICHAELS, MARK L.,XU, JING,ELLISON, MURIELLE M.
申请号:
CA2739615
公开号:
CA2739615C
申请日:
2009.10.08
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The invention provides nucleic acid molecules encoding FGF21 mutantpolypeptides, FGF21mutant polypeptides, comprising extended in vivo half-lives, pharmaceuticalcompositionscomprising FGF21 mutant polypeptides having extended in vivo half-lives, andmethods fortreating metabolic disorders using such nucleic acids, polypeptides, orpharmaceuticalcompositions.