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Polypeptide(s) transporté(s) par CYAA et utilisation pour induire des réponses immunes tant thérapeutiques que prophylactiques
专利权人:
GENTICEL
发明人:
申请号:
EP11305069.4
公开号:
EP2478915A1
申请日:
2011.01.24
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The invention is directed to means, based on CyaA-carried polypeptide(s), for use in the immunotherapeutic treatment of first determined pathological condition(s) diagnosed in a mammalian host by eliciting a T cell immune response against a first group of epitopes contained in said polypeptide(s) and in the prophylaxis against second determined pathological condition(s) in the same mammalian host by eliciting a T cell memory immune response against a second group of epitopes contained in said polypeptide(s), said immune responses being obtained after administration of said vector-carried polypeptide(s) into said host, wherein said prophylaxis against second determined pathological condition(s) is not observed when said second group of epitopes is not contained in said administered vector-carried polypeptide(s).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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