BASTOS CECILIA,BOOKER MICHAEL L,CELATKA CASSANDRA A,CLARDY JON C,CORTESE JOSEPH,PATEL VISHAL P,SKERLJ RENATO,WIEGAND ROGER C,WIRTH DYANN F
申请号：
IN7857/DELNP/2010
公开号：
IN2010DN07857A
申请日:
2010.11.08
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
Inhibitors of dihydroorotate dehydrogenase (DHODH) for the Plasmodium enzyme have been identified and characterized. The inhibitors have high specificity, submicromolar efficacy against cultured parasite strains, exhibit drug-like properties, and are not overtly cytotoxic.
